Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473768 | 0.95 | SLC6A2 (0.41) | HTR6PTGER4SCARB1ELANESLC6A2 | |
| SCHEMBL8474562 | 0.89 | MAPK1 (0.38) | PTGER4SLC6A2SLC6A3SLC6A4KDM4E | |
| SCHEMBL8475106 | 0.89 | HTR6 (0.41) | HTR6PTGER4KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8475897 | 0.88 | NPY1R (0.38) | SLC6A2SLC6A3SLC6A4KDM4EALDH1A1 | |
| SCHEMBL8474898 | 0.88 | EGFR (0.40) | L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL8473195 | 0.87 | HTR6 (0.38) | HTR6KDM4EALDH1A1 | |
| SCHEMBL8477374 | 0.83 | PTGER4 (0.51) | PTGER4ELANEKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8475375 | 0.82 | PTGER4 (0.50) | PTGER4ELANEKDM4EALDH1A1LMNA | |
| SCHEMBL8472629 | 0.82 | CACNA2D1 (0.40) | HTR6KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8473693 | 0.81 | MAPK1 (0.41) | HTR6KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |