Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474562 | 0.95 | MAPK1 (0.38) | NPY1RGPR88HRH2PPARGPPARD | |
| SCHEMBL8473768 | 0.91 | SLC6A2 (0.41) | KDM4EALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL8474898 | 0.91 | EGFR (0.40) | NPY1RGPR88LMNAL3MBTL1 | |
| SCHEMBL8901044 | 0.91 | NPY1R (0.41) | NPY1RGPR88HRH2KDM4EALDH1A1 | |
| SCHEMBL8477377 | 0.88 | HTR6 (0.39) | KDM4EALDH1A1LMNAL3MBTL1SLC6A2 | |
| SCHEMBL8475899 | 0.86 | HRH3 (0.45) | KDM4EALDH1A1LMNATP53MAPT | |
| SCHEMBL8477090 | 0.86 | NPY1R (0.40) | NPY1RGPR88HRH2KDM4EALDH1A1 | |
| SCHEMBL8473410 | 0.84 | MAPK1 (0.43) | NPY1RGPR88KDM4EALDH1A1LMNA | |
| SCHEMBL8477348 | 0.83 | GPR88 (0.41) | NPY1RGPR88PPARGPPARDPPARA | |
| SCHEMBL8475904 | 0.82 | SLC6A3 (0.41) | GPR88ALDH1A1LMNASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |