Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474816 | 0.93 | PGR (0.46) | PGRALDH1A1MAPK8KDM4ERECQL | |
| SCHEMBL8474424 | 0.84 | PGR (0.49) | PGRALDH1A1MAPK8KDM4ERECQL | |
| SCHEMBL8477593 | 0.84 | PGR (0.44) | PGRALDH1A1MAPK8KDM4ERECQL | |
| SCHEMBL8471731 | 0.84 | PGR (0.46) | PGRALDH1A1MAPK8KDM4ERECQL | |
| SCHEMBL8472327 | 0.83 | PGR (0.52) | PGRALDH1A1MAPK8KDM4ERECQL | |
| SCHEMBL8473957 | 0.70 | RORA (0.45) | PGRALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL7654816 | 0.69 | PGR (0.55) | PGRALDH1A1MAPK8KDM4ERECQL | |
| SCHEMBL8473019 | 0.69 | PGR (0.45) | PGRALDH1A1MAPK8KDM4ERECQL | |
| SCHEMBL8475762 | 0.68 | OXER1 (0.38) | PGRALDH1A1MAPK8KDM4ESMN1; SMN2 | |
| SCHEMBL30485670 | 0.68 | PGR (0.68) | PGRALDH1A1MAPK8KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908844-A | N-substituted azabicycloalkane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-01 | — | — | US | disclosed |