Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | BID | P55957 | 4/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503737 | 0.86 | MMP2 (0.44) | MMP2FOLH1CA12CA1CA2 | |
| SCHEMBL3738295 | 0.85 | CA12 (0.48) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL8477659 | 0.84 | MMP2 (0.42) | MMP2FOLH1CA12CA1CA2 | |
| SCHEMBL321003 | 0.84 | GABRA1 (0.45) | MMP2CA12CA1CA2CA7 | |
| SCHEMBL17627459 | 0.82 | MMP2 (0.41) | MMP2FOLH1CA12CA1CA2 | |
| SCHEMBL28874207 | 0.82 | MMP2 (0.41) | MMP2FOLH1CA12CA1CA2 | |
| SCHEMBL15597720 | 0.82 | MMP2 (0.41) | MMP2FOLH1CA12CA1CA2 | |
| SCHEMBL19628955 | 0.82 | FOLH1 (0.44) | MMP2FOLH1CA12CA1CA2 | |
| SCHEMBL7781034 | 0.82 | MMP2 (0.41) | MMP2FOLH1CA12CA1CA2 | |
| SCHEMBL1000014 | 0.80 | MMP2 (0.54) | MMP2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856334-A | ANTAGONIST FOR EOSINOPHILS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0773219-A1 | IMIDAZOQUINOLINE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |