Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | BID | P55957 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489825 | 0.87 | BID (0.51) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL20503737 | 0.86 | MMP2 (0.44) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL423306 | 0.85 | GABRA1 (0.54) | GABRA1GABRB2BIDMCL1PPARA | |
| SCHEMBL8477665 | 0.84 | MMP2 (0.42) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL8477659 | 0.84 | MMP2 (0.42) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL10489741 | 0.84 | BID (0.60) | GABRA1GABRB2BIDMCL1PPARA | |
| SCHEMBL10489945 | 0.83 | GABRA1 (0.50) | GABRA1GABRB2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3260662 | 0.83 | BID (0.68) | BIDMCL1PPARABCL2L1BAK1 | |
| SCHEMBL19628955 | 0.82 | FOLH1 (0.44) | BIDMCL1BCL2L1BAK1MMP2 | |
| SCHEMBL28874207 | 0.82 | MMP2 (0.41) | BIDMCL1PPARABCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108976140-B | Preparation method and intermediate of 2-amino-6-ethylbenzoic acid | 上海医药工业研究院 | 2021-07-09 | — | — | CN | claimed |
| CN-108976140-A | A kind of Preparation Method And Their Intermediate of 2- amino -6- ethyl benzoate | 上海医药工业研究院 | 2018-12-11 | — | — | CN | claimed |
| WO-2011054874-A1 | METHOD FOR THE PREPARATION OF 2-AMINO-6-ETHYLBENZOIC ACID | ACTIVE BIOTECH AB (SE) | 2011-05-12 | — | — | WO | claimed |
| EP-2316818-A1 | Method for the preparation of 2-amino-6-ethylbenzoic acid | Active Biotech AB (SE) | 2011-05-04 | — | — | EP | claimed |
| CN-115613352-A | Breathable down-proof fabric and preparation method thereof | 余翔 | 2023-01-17 | — | — | CN | disclosed |
| CN-108976140-B | Preparation method and intermediate of 2-amino-6-ethylbenzoic acid | 上海医药工业研究院 | 2021-07-09 | — | — | CN | disclosed |
| CN-108976140-B | Preparation method and intermediate of 2-amino-6-ethylbenzoic acid | 上海医药工业研究院 | 2021-07-09 | — | — | CN | disclosed |
| CN-108976140-B | Preparation method and intermediate of 2-amino-6-ethylbenzoic acid | 上海医药工业研究院 | 2021-07-09 | — | — | CN | disclosed |
| US-10350315-B2 | Quinoline-3-carboxamide compounds and their use in diagnosis | Westfaelische Wihelms-Universitaet Muenster (DE) | 2019-07-16 | — | — | US | disclosed |
| US-10350315-B2 | Quinoline-3-carboxamide compounds and their use in diagnosis | Westfaelische Wihelms-Universitaet Muenster (DE) | 2019-07-16 | — | — | US | disclosed |
| CN-108976140-A | A kind of Preparation Method And Their Intermediate of 2- amino -6- ethyl benzoate | 上海医药工业研究院 | 2018-12-11 | — | — | CN | disclosed |
| CN-108976140-A | A kind of Preparation Method And Their Intermediate of 2- amino -6- ethyl benzoate | 上海医药工业研究院 | 2018-12-11 | — | — | CN | disclosed |
| EP-0322133-A1 | Quinazoline derivatives | SmithKline Beecham Intercredit B.V. (NL) | 1989-06-28 | — | — | EP | disclosed |
| WO-1989005297-A1 | COMPOUNDS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-06-15 | — | — | WO | disclosed |
| CN-1033380-A | Compound | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1989-06-14 | — | — | CN | disclosed |
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |
| US-4665070-A | SERINE PROTEINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1987-05-12 | — | — | US | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0206323-A1 | 2-Oxy-4H-3,1-benzoxazin-4-one derivatives and related compounds | SYNTEX (U.S.A.) INC. (US) | 1986-12-30 | — | — | EP | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10350315-B2 | Quinoline-3-carboxamide compounds and their use in diagnosis | S100A9, S100A4, S100A10 | GABRA1 3049/4885GABRB2 2569/4885BID 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.