Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478822 | 0.85 | BACE1 (0.31) | BACE1 | |
| SCHEMBL456605 | 0.82 | — | — | |
| SCHEMBL27907822 | 0.77 | BACE1 (0.34) | BACE1 | |
| SCHEMBL8478340 | 0.70 | — | — | |
| SCHEMBL27926217 | 0.69 | BACE1 (0.31) | BACE1 | |
| SCHEMBL27908057 | 0.69 | BACE1 (0.34) | BACE1 | |
| SCHEMBL15063867 | 0.68 | GRIN2D (0.31) | — | |
| SCHEMBL15063570 | 0.68 | SIGMAR1 (0.30) | — | |
| SCHEMBL15063831 | 0.68 | GABRA1 (0.33) | — | |
| SCHEMBL11687281 | 0.68 | ALDH1A1 (0.39) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |