Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | SI | P14410 | 4/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474261 | 0.86 | MGAM (0.42) | MGAMGAASIMGAM2MRGPRX4 | |
| SCHEMBL8478958 | 0.85 | MGAM (0.46) | MGAMGAASIMGAM2MRGPRX4 | |
| SCHEMBL8480995 | 0.82 | PTGS2 (0.35) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL8478292 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8477816 | 0.80 | GAA (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8480887 | 0.79 | GAA (0.43) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL8475146 | 0.73 | MGAM (0.42) | MGAMGAASIMGAM2MRGPRX4 | |
| SCHEMBL8474934 | 0.70 | BCL2L2 (0.33) | GAAKDM4EMAPTMAPK1ERN1 | |
| SCHEMBL8479650 | 0.70 | TLR8 (0.36) | MGAMGAASIMGAM2FFAR1 | |
| SCHEMBL13802180 | 0.69 | MAOB (0.60) | ALDH1A1LMNAMAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |