Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SI | P14410 | 3/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474699 | 0.86 | MAPT (0.37) | MGAMGAASIMGAM2HPGD | |
| SCHEMBL8475020 | 0.83 | NPSR1 (0.40) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8475256 | 0.82 | L3MBTL1 (0.40) | MGAMGAASIMGAM2PTPN1 | |
| SCHEMBL8476444 | 0.78 | HPGD (0.36) | MGAMGAASIMGAM2HPGD | |
| SCHEMBL8478485 | 0.77 | MGAM (0.36) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL8474433 | 0.77 | MGAM (0.39) | MGAMGAASIMGAM2 | |
| SCHEMBL8480653 | 0.77 | SLC10A2 (0.39) | HPGDKDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL8481462 | 0.75 | MGAM (0.42) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL8480711 | 0.74 | MGAM (0.43) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL8474261 | 0.74 | MGAM (0.42) | MGAMGAASIMGAM2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |