Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474934 | 0.84 | BCL2L2 (0.33) | PTGS2PTGS1ERN1TTRMAPT | |
| SCHEMBL8479650 | 0.83 | TLR8 (0.36) | PTGS2PTGS1ERN1TTRGAA | |
| SCHEMBL8477755 | 0.82 | MGAM (0.46) | ERN1MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL8479978 | 0.79 | PDE4B (0.36) | PTGS2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL8474261 | 0.69 | MGAM (0.42) | MAPTGAAKDM4EALDH1A1HPGD | |
| SCHEMBL8478958 | 0.69 | MGAM (0.46) | ERN1MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL8481674 | 0.68 | PTGS2 (0.37) | PTGS2PTGS1MAPTGAAKDM4E | |
| SCHEMBL1911833 | 0.67 | LTA4H (0.57) | ERN1TTRKDM4EALDH1A1TDP1 | |
| SCHEMBL7936555 | 0.67 | HTR2C (0.52) | PTGS2PTGS1MAPTKDM4ETNKS2 | |
| SCHEMBL29644376 | 0.67 | KDM4E (0.54) | MAPTGAAKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |