Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325472 | 0.89 | ITGB3 (0.47) | USP28SIRT2SIRT1SIRT3NPC1 | |
| SCHEMBL7445049 | 0.78 | MAPT (0.62) | SIRT2SIRT1SIRT3NPC1MAPT | |
| Pyridine SCHEMBL8631988 | 0.77 | SIRT2 (0.47) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL8321319 | 0.73 | ITGB3 (0.51) | SIRT2SIRT1SIRT3NPC1ITGB3 | |
| SCHEMBL7445054 | 0.73 | MCHR1 (0.49) | MAPTKMT2AMEN1HSD17B10ALOX15 | |
| SCHEMBL24891825 | 0.73 | RAB9A (0.64) | NPC1ITGB3ITGA2BMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7437697 | 0.72 | MCHR1 (0.48) | MAPTKMT2AMEN1HSD17B10ALOX15 | |
| SCHEMBL8318988 | 0.72 | MAPT (0.57) | NPC1ITGB3ITGA2BITGA2MAPT | |
| SCHEMBL8661696 | 0.72 | MAPT (0.47) | NPC1MAPTKMT2AMEN1NPSR1 | |
| Hydrochloric Acid SCHEMBL8580184 | 0.71 | MAPT (0.46) | ITGB3ITGA2BITGA2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990107-A | ADMINISTERING TO INHIBIT THE BINDING OF FIBRINOGEN TO BLOOD PLATELETS IN A MAMMAL; OR TO INHIBIT OSTEOCLAST MEDIATED BONE RESORPTION | MERCK & CO., INC. (US) | 1999-11-23 | — | — | US | disclosed |