Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 1/20 | 0.39 |
| ▸ | HEXB | P07686 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478421 | 0.86 | ALDH1A1 (0.36) | HEXAHEXBUSP7PTGS2PTGS1 | |
| SCHEMBL8477966 | 0.84 | DHFR (0.38) | HEXAHEXBUSP7PTGS2PTGS1 | |
| SCHEMBL8474671 | 0.83 | BACE1 (0.33) | HEXAHEXBUSP7PTGS2PTGS1 | |
| SCHEMBL3347947 | 0.76 | SYK (0.33) | HEXAHEXBUSP7 | |
| SCHEMBL2834322 | 0.76 | PTGS2 (0.35) | HEXAHEXBPTGS2PTGS1 | |
| SCHEMBL8480572 | 0.74 | USP7 (0.35) | HEXAHEXBUSP7 | |
| SCHEMBL8473979 | 0.70 | DHFR (0.34) | HEXAHEXBPTGS2PTGS1GCGR | |
| SCHEMBL8479825 | 0.69 | USP7 (0.33) | HEXAHEXBUSP7 | |
| SCHEMBL15519390 | 0.69 | PTGS2 (0.47) | HEXAHEXBPTGS2PTGS1 | |
| SCHEMBL7456929 | 0.68 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |