Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477680 | 0.84 | SMN1; SMN2 (0.40) | RIPK1SLC6A2NR3C2HTTSMN1; SMN2 | |
| SCHEMBL8475579 | 0.80 | CA12 (0.34) | MAPK1CA12CA1CA2CA4 | |
| SCHEMBL8474416 | 0.80 | TAAR1 (0.32) | SLC6A2MAPK1TAAR1 | |
| SCHEMBL8859966 | 0.74 | HTR1A (0.43) | SMN1; SMN2 | |
| SCHEMBL8480296 | 0.73 | TAAR1 (0.42) | SLC6A2MAPK1KCNA5TAAR1ALDH1A1 | |
| SCHEMBL8475142 | 0.72 | CYP19A1 (0.35) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL27588489 | 0.72 | IDO1 (0.46) | CA12CA1CA2CA4CA7 | |
| SCHEMBL8477543 | 0.72 | MEN1 (0.42) | SLC6A2IDO1 | |
| SCHEMBL456067 | 0.71 | TAAR1 (0.37) | MAPK1CA12CA1CA2CA4 | |
| SCHEMBL8476329 | 0.70 | KMT2A (0.44) | SLC6A2TAAR1HTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |