Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | VDR | P11473 | 5/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477930 | 0.85 | CYP19A1 (0.40) | CYP19A1KDM4ECASP1HSD17B10VDR | |
| SCHEMBL8480430 | 0.84 | CYP19A1 (0.38) | CYP19A1KDM4ECASP1HSD17B10VDR | |
| SCHEMBL8479047 | 0.81 | CYP19A1 (0.38) | CYP19A1KDM4ECASP1HSD17B10VDR | |
| SCHEMBL8581100 | 0.78 | CYP19A1 (0.38) | CYP19A1KDM4ECASP1HSD17B10VDR | |
| SCHEMBL8474472 | 0.77 | VDR (0.37) | CYP19A1KDM4ECASP1HSD17B10VDR | |
| SCHEMBL8474416 | 0.76 | TAAR1 (0.32) | MEN1KMT2AESR1 | |
| SCHEMBL8478244 | 0.72 | RIPK1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8647874 | 0.72 | VDR (0.44) | CYP19A1KDM4EVDRGAATAS1R3 | |
| SCHEMBL8477431 | 0.71 | CYP19A1 (0.43) | CYP19A1CASP1HSD17B10VDRFFAR1 | |
| SCHEMBL8475300 | 0.70 | LMNA (0.37) | HSD17B10RECQLALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |