Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478244 | 0.84 | RIPK1 (0.34) | SMN1; SMN2HTTSLC6A2RIPK1NR3C2 | |
| SCHEMBL8481475 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTMEN1KMT2ASLC6A2 | |
| SCHEMBL8477307 | 0.80 | MEN1 (0.38) | SMN1; SMN2HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL8477930 | 0.73 | CYP19A1 (0.40) | HTTMEN1KMT2ASLC6A2LMNA | |
| SCHEMBL8859966 | 0.73 | HTR1A (0.43) | SMN1; SMN2CYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL8475300 | 0.72 | LMNA (0.37) | SMN1; SMN2HTTLMNANPSR1KIF11 | |
| SCHEMBL2480627 | 0.72 | PDE4A (0.44) | CYP1A2LMNA | |
| SCHEMBL27588489 | 0.71 | IDO1 (0.46) | GAACHRM2CHRM1 | |
| SCHEMBL8477543 | 0.71 | MEN1 (0.42) | MEN1KMT2ASLC6A2CYP1A2CYP3A4 | |
| SCHEMBL9458722 | 0.71 | LMNA (0.40) | MEN1KMT2ASLC6A2LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |