Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474107 | 0.91 | LTA4H (0.34) | LTA4HESR1ESR2MEN1KMT2A | |
| SCHEMBL8475444 | 0.90 | LTA4H (0.41) | LTA4HESR1ESR2ABL1ABCB1 | |
| SCHEMBL8474291 | 0.85 | MGAM (0.43) | ABCB1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8474934 | 0.82 | BCL2L2 (0.33) | MEN1KMT2AMAPTGAA | |
| SCHEMBL8478847 | 0.80 | LTA4H (0.34) | LTA4HESR1ESR2MEN1KMT2A | |
| SCHEMBL8474594 | 0.79 | RHEB (0.35) | LTA4HMEN1KMT2AALDH1A1GSTP1 | |
| SCHEMBL8480621 | 0.79 | FFAR4 (0.33) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL8476457 | 0.79 | HTT (0.33) | LTA4HMEN1KMT2ANPBWR1GSTP1 | |
| SCHEMBL8474577 | 0.75 | MGAM (0.46) | LTA4HABCB1BACE1MEN1KMT2A | |
| SCHEMBL8476328 | 0.75 | PDE4B (0.40) | RAB9ANPC1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |