Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.40 |
| ▸ | PDE4A | P27815 | 5/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.40 |
| ▸ | MGAM | O43451 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | SI | P14410 | 5/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477677 | 0.88 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL8477540 | 0.88 | PDE4B (0.42) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL8475248 | 0.87 | MGAM (0.33) | MGAMGAASIMGAM2GCGR | |
| SCHEMBL8474110 | 0.80 | GCGR (0.35) | NPC1RAB9AADORA3ADORA2AADORA1 | |
| SCHEMBL8474107 | 0.77 | LTA4H (0.34) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8479313 | 0.76 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL8476879 | 0.75 | GAA (0.40) | MGAMGAASIMGAM2 | |
| SCHEMBL8478249 | 0.75 | LTA4H (0.41) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL8479825 | 0.75 | USP7 (0.33) | MGAMGAASIMGAM2 | |
| SCHEMBL8475575 | 0.75 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |