Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527700 | 0.95 | ADRB2 (0.41) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL27475653 | 0.92 | DNM1 (0.45) | DNM1TSHRALDH1A1USP2 | |
| SCHEMBL28873662 | 0.92 | ADRB2 (0.39) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL27471804 | 0.90 | DNM1 (0.48) | DNM1TSHRUSP2 | |
| SCHEMBL2333903 | 0.89 | HSD17B10 (0.32) | — | |
| SCHEMBL28105324 | 0.88 | TSHR (0.50) | DNM1TSHRHPGDALDH1A1LMNA | |
| SCHEMBL1665116 | 0.87 | ADRB2 (0.36) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL6179383 | 0.86 | DNM1 (0.48) | DNM1TSHRALDH1A1CA1CA2 | |
| SCHEMBL11312612 | 0.85 | ADRB2 (0.35) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL6178129 | 0.84 | DNM1 (0.52) | DNM1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1130351-C | 1,5-benzodiazepine derivatives | ZERIA PHARM CO LTD (JP) | 2003-12-10 | — | — | CN | disclosed |
| CN-1246850-A | 1,5-benzodiazepine derivatives | ZERIA PHARM CO LTD (JP) | 2000-03-08 | — | — | CN | disclosed |
| US-5885934-A | HERBICIDES OR FOR THE DESICCATION/DEFOLIATION OF PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| CN-1158122-A | Substituted triazolinones as plant protective agents | BASF AG (DE) | 1997-08-27 | — | — | CN | disclosed |
| WO-1996005179-A1 | SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-22 | — | — | WO | disclosed |
| WO-1994011344-A1 | SUBSTITUTED 3,4,5,6-TETRAHYDROPHTHALIMIDES FOR USE AS HERBICIDES AND/OR DEFOLIANTS OR DESICCANTS | BASF AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |