Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369002 | 1.00 | PKM (0.40) | PKMGAATSHRPOLBLMNA | |
| SCHEMBL13472614 | 0.85 | POLB (0.43) | PKMGAATSHRPOLBALDH1A1 | |
| SCHEMBL7366326 | 0.80 | PKM (0.44) | PKMGAAL3MBTL1BRD4KMT2A | |
| SCHEMBL7366324 | 0.80 | PKM (0.44) | PKMGAAL3MBTL1BRD4KMT2A | |
| SCHEMBL7311432 | 0.78 | PKM (0.45) | PKMGAALMNAL3MBTL1BRD4 | |
| SCHEMBL7311444 | 0.78 | PKM (0.45) | PKMGAALMNAL3MBTL1BRD4 | |
| SCHEMBL12788439 | 0.78 | POLB (0.42) | PKMGAATSHRPOLBALDH1A1 | |
| SCHEMBL7296969 | 0.74 | PLA2G10 (0.43) | PKMGAAPOLBL3MBTL1BRD4 | |
| SCHEMBL7296978 | 0.74 | PLA2G10 (0.43) | PKMGAAPOLBL3MBTL1BRD4 | |
| SCHEMBL26097101 | 0.73 | TSHR (0.54) | TSHRPOLBLMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |