Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335782 | 1.00 | CTSB (0.41) | CTSBCTSSCTSLCYP3A4CYP2C19 | |
| SCHEMBL7862909 | 0.76 | PPID (0.43) | CYP3A4CYP2C19MEN1KMT2AKDM4E | |
| SCHEMBL30683853 | 0.69 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL27994909 | 0.68 | MEN1 (0.49) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL24457722 | 0.67 | SIGMAR1 (0.63) | CYP3A4CYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL4837691 | 0.66 | CTSC (0.49) | CTSSMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9585875 | 0.66 | CYP4F2 (0.57) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5722434 | 0.66 | MEN1 (0.43) | CTSBCTSSCYP3A4CYP2C19MEN1 | |
| SCHEMBL13904680 | 0.66 | CTSB (0.43) | CTSBCTSSCTSLCYP3A4ALDH1A1 | |
| SCHEMBL7733774 | 0.66 | MAPT (0.55) | CYP2C19MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948935-A | Process and intermediates for (s)-α-amino-1-carboxycyclopentaneacetic acid | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1999-09-07 | — | — | US | disclosed |