Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611749 | 0.80 | CYP3A4 (0.40) | SMN1; SMN2OPRM1KDM4EALDH1A1ANPEP | |
| SCHEMBL7619724 | 0.80 | CYP3A4 (0.40) | SMN1; SMN2OPRM1KDM4EALDH1A1ANPEP | |
| SCHEMBL7614988 | 0.80 | CYP3A4 (0.40) | SMN1; SMN2OPRM1KDM4EALDH1A1ANPEP | |
| SCHEMBL7864103 | 0.80 | CYP3A4 (0.43) | SMN1; SMN2LMNAOPRM1KDM4EALDH1A1 | |
| SCHEMBL7614012 | 0.80 | CYP3A4 (0.40) | SMN1; SMN2OPRM1KDM4EALDH1A1ANPEP | |
| SCHEMBL7613269 | 0.80 | CYP3A4 (0.40) | SMN1; SMN2OPRM1KDM4EALDH1A1ANPEP | |
| SCHEMBL7614073 | 0.76 | L3MBTL1 (0.42) | ATMSMN1; SMN2L3MBTL1LMNAALDH1A1 | |
| SCHEMBL8335782 | 0.76 | CTSB (0.41) | KDM4EALDH1A1MAPTANPEPMEN1 | |
| SCHEMBL8478313 | 0.76 | CTSB (0.41) | KDM4EALDH1A1MAPTANPEPMEN1 | |
| SCHEMBL7957020 | 0.74 | OPRM1 (0.38) | SMN1; SMN2LMNAOPRM1ANPEPOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1148047-A2 | Processes for preparing cyclic compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-6218548-B1 | (TRIARYLMETHYL)AMINOSPIROPYRROLES | DAIICHI PAHARMACEUTICAL CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| US-6013806-A | ANTIBACTEIRAL | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-01-11 | — | — | US | disclosed |
| US-5856518-A | Production process of cyclic compound | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0829473-A1 | PROCESSES FOR PREPARING CYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |