Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 18/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760902 | 0.71 | LSS (0.75) | LSS | |
| SCHEMBL8478402 | 0.69 | CASR (0.40) | LSSCASR | |
| SCHEMBL8483830 | 0.66 | LSS (0.49) | LSS | |
| SCHEMBL8483920 | 0.65 | LSS (0.51) | LSS | |
| SCHEMBL8482871 | 0.64 | LSS (0.50) | LSS | |
| SCHEMBL8485033 | 0.64 | LSS (0.49) | LSS | |
| SCHEMBL8478939 | 0.63 | LSS (0.48) | LSS | |
| SCHEMBL6440270 | 0.58 | LSS (0.34) | LSS | |
| SCHEMBL7794822 | 0.56 | RAB9A (0.56) | — | |
| SCHEMBL7856810 | 0.56 | RAB9A (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |