Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481210 | 0.88 | CNR1 (0.57) | KMT2ACNR1CNR2ALDH1A1SLC6A9 | |
| Hydrochloric Acid SCHEMBL5394384 | 0.87 | CNR1 (0.56) | KMT2ACNR1CNR2ALDH1A1LMNA | |
| SCHEMBL25882268 | 0.86 | LMNA (0.47) | KMT2AALDH1A1LMNAMEN1GLA | |
| SCHEMBL12499368 | 0.84 | ALDH1A1 (0.51) | KMT2ACNR1CNR2ALDH1A1TDP1 | |
| SCHEMBL2475044 | 0.82 | KMT2A (0.56) | KMT2ACNR1CNR2ALDH1A1LMNA | |
| SCHEMBL8473590 | 0.81 | ALDH1A1 (0.60) | KMT2ACNR1CNR2ALDH1A1TDP1 | |
| SCHEMBL18614900 | 0.80 | L3MBTL3 (0.50) | KMT2ACNR1CNR2ALDH1A1SLC6A9 | |
| SCHEMBL18614904 | 0.80 | L3MBTL3 (0.50) | KMT2ACNR1CNR2ALDH1A1SLC6A9 | |
| SCHEMBL18634599 | 0.80 | L3MBTL3 (0.50) | KMT2ACNR1CNR2ALDH1A1SLC6A9 | |
| SCHEMBL5392078 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TDP1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872115-A | COMPOUNDS FOR TREATMENT OF HYPERCHOLESTEROLEMIA, ISCHEMIC HEART DISEASE, CEREBROVASCULAR DISEASE OR ATHEROSCLEROSIS | GRELAN PHARMACEUTICAL CO. LTD. (JP) | 1999-02-16 | — | — | US | disclosed |