Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480899 | 0.92 | MAPT (0.37) | MAPTDCTPP1PTGS2ESR1ESR2 | |
| SCHEMBL8480055 | 0.90 | ESR1 (0.36) | MAPTPTGS2ESR1ESR2KDM4E | |
| SCHEMBL8477572 | 0.84 | KDM4E (0.30) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8479657 | 0.82 | PREP (0.38) | MAPTPTGS2ESR1ESR2KDM4E | |
| SCHEMBL8478143 | 0.81 | PTGS2 (0.42) | PTGS2ESR1ESR2MEN1KMT2A | |
| SCHEMBL8475809 | 0.77 | MAPT (0.38) | MAPTDCTPP1PTGS2ESR1ESR2 | |
| SCHEMBL8478779 | 0.76 | ALDH1A1 (0.32) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8474843 | 0.75 | KDM4E (0.39) | MAPTPTGS2KDM4EALDH1A1MEN1 | |
| SCHEMBL8477582 | 0.74 | MAPT (0.38) | MAPTDCTPP1PTGS2ESR1ESR2 | |
| SCHEMBL8474773 | 0.74 | MAPT (0.38) | MAPTDCTPP1PTGS2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |