Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476637 | 0.90 | ITGB2 (0.33) | MAPTBRD4BRD2PTGS2PTGS1 | |
| SCHEMBL8474502 | 0.80 | PTGS1 (0.33) | HPGDMAPTPTGS2PTGS1 | |
| SCHEMBL8478779 | 0.77 | ALDH1A1 (0.32) | HPGDMAPTSMN1; SMN2 | |
| SCHEMBL8475633 | 0.74 | TDP1 (0.31) | TDP1 | |
| SCHEMBL12815787 | 0.72 | MAPT (0.36) | MAPTBRD4BRD2PTGS2PTGS1 | |
| SCHEMBL12815928 | 0.71 | MAPT (0.35) | MAPTBRD4BRD2PTGS2PTGS1 | |
| SCHEMBL8478736 | 0.70 | PTGS1 (0.33) | HPGDMAPTPTGS2PTGS1TDP1 | |
| SCHEMBL8480278 | 0.69 | ACHE (0.38) | MAPTBRD4BRD2PTGS2PTGS1 | |
| SCHEMBL7533650 | 0.67 | MAPT (0.35) | MAPTBRD4BRD2PTGS2PTGS1 | |
| SCHEMBL8481612 | 0.67 | MAPT (0.35) | TP53MAPTBRD4BRD2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |