Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478779 | 0.86 | ALDH1A1 (0.32) | — | |
| SCHEMBL8478143 | 0.83 | PTGS2 (0.42) | ESR1ESR2 | |
| SCHEMBL8477572 | 0.77 | KDM4E (0.30) | — | |
| SCHEMBL8478609 | 0.74 | TP53 (0.34) | TDP1 | |
| SCHEMBL8478736 | 0.74 | PTGS1 (0.33) | TDP1ESR1ESR2 | |
| SCHEMBL8474276 | 0.70 | TDP1 (0.34) | TDP1 | |
| SCHEMBL8476215 | 0.70 | PDE4B (0.42) | TDP1 | |
| SCHEMBL8479432 | 0.68 | GCGR (0.41) | TDP1ESR1ESR2 | |
| SCHEMBL8481471 | 0.67 | PDE4B (0.46) | TDP1 | |
| SCHEMBL8476637 | 0.65 | ITGB2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |