Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 6/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.37 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846022 | 0.81 | TRPV1 (0.43) | TNKSTNKS2ALDH1A1NPC1RAB9A | |
| SCHEMBL22410629 | 0.74 | MAPT (0.39) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL845787 | 0.74 | TNKS (0.43) | TNKSTNKS2ALDH1A1NPC1RAB9A | |
| SCHEMBL846354 | 0.73 | TRPV1 (0.44) | TNKSTNKS2NPC1RAB9AMAPT | |
| SCHEMBL2719453 | 0.73 | SMN1; SMN2 (0.44) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL845882 | 0.71 | TRPV1 (0.43) | ALDH1A1NPC1RAB9ACHRNB4CHRNA3 | |
| SCHEMBL847871 | 0.71 | MCHR1 (0.42) | TNKSTNKS2ALDH1A1NPC1RAB9A | |
| SCHEMBL845899 | 0.66 | TRPV1 (0.47) | ALDH1A1NPC1RAB9ACHRNB4CHRNA3 | |
| SCHEMBL846941 | 0.66 | RAB9A (0.59) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL20819772 | 0.66 | PDK1 (0.36) | ALDH1A1NPC1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603883-B1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-28 | — | — | EP | claimed |