Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482377 | 0.86 | L3MBTL1 (0.40) | MEN1KMT2A | |
| SCHEMBL8482577 | 0.83 | S1PR1 (0.36) | ITGB3ITGA2BS1PR1MEN1KMT2A | |
| SCHEMBL8478303 | 0.82 | ITGB3 (0.39) | ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL8478330 | 0.81 | KDM1A (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8541621 | 0.79 | ALDH1A1 (0.50) | DRD2MEN1KMT2AALDH1A1 | |
| SCHEMBL8478639 | 0.79 | MAPT (0.36) | ALDH1A1 | |
| SCHEMBL8505430 | 0.78 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL8478027 | 0.78 | KCNH2 (0.41) | KMT2A | |
| SCHEMBL8477737 | 0.78 | MAPT (0.40) | ALDH1A1 | |
| SCHEMBL8483053 | 0.78 | MAPT (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5871709-A | TETRAAZACYCLODODECANE COMPOUNDS SUBSTITUTED WITH ALKYL CARBOXY COMPOUNDS FOR CARDIOVASCULAR DISORDERS AND BRAIN TUMORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |