Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 7/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665212 | 0.96 | CCR3 (0.39) | CCR3MCHR1NPSR1SLC6A12TMEM97 | |
| SCHEMBL8500943 | 0.93 | CCR3 (0.36) | CCR3MCHR1NPSR1SLC6A12TMEM97 | |
| SCHEMBL8484139 | 0.87 | NTRK1 (0.36) | RET | |
| SCHEMBL8484431 | 0.84 | L3MBTL1 (0.35) | KMT2A | |
| SCHEMBL8483741 | 0.83 | CCR3 (0.44) | CCR3MCHR1NPSR1SLC6A12TMEM97 | |
| SCHEMBL8669574 | 0.83 | KDM4D (0.36) | RET | |
| SCHEMBL8485533 | 0.83 | NPSR1 (0.42) | CCR3MCHR1NPSR1SLC6A12TMEM97 | |
| SCHEMBL8666043 | 0.81 | HTT (0.33) | — | |
| SCHEMBL8648475 | 0.81 | CCR3 (0.39) | CCR3MCHR1HTR7 | |
| SCHEMBL8479385 | 0.81 | DPP4 (0.38) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |