Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484431 | 0.96 | L3MBTL1 (0.35) | HTTL3MBTL1JAK2JAK3LMNA | |
| SCHEMBL8504363 | 0.94 | KCNA5 (0.30) | — | |
| SCHEMBL8479385 | 0.87 | DPP4 (0.38) | C5AR1 | |
| SCHEMBL8665212 | 0.83 | CCR3 (0.39) | — | |
| SCHEMBL8479703 | 0.81 | CCR3 (0.42) | — | |
| SCHEMBL8669574 | 0.80 | KDM4D (0.36) | — | |
| SCHEMBL8500943 | 0.80 | CCR3 (0.36) | — | |
| SCHEMBL8666049 | 0.79 | L3MBTL1 (0.34) | HTTL3MBTL1LMNAMAPK1 | |
| SCHEMBL8484139 | 0.79 | NTRK1 (0.36) | — | |
| SCHEMBL8504386 | 0.77 | NTRK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |