SCHEMBL8480167

SCHEMBL8480167

CCCc1[c]c(-c2ccc(C)cc2)c(C)c(-c2ccc(C)cc2)c1C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DPP4 P27487 1/20 0.32
GCGR P47871 1/20 0.31
HEXA P06865 1/20 0.31
HEXB P07686 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8481067 0.87 GCGR (0.33) ALDH1A1SMN1; SMN2GCGR
SCHEMBL8479336 0.85 GCGR (0.31) GCGR
SCHEMBL8477582 0.84 MAPT (0.38) GAAHEXAHEXB
SCHEMBL8479901 0.83
SCHEMBL8475352 0.76 KMT2A (0.36) ALDH1A1GAASMN1; SMN2
SCHEMBL8482102 0.75 GCGR (0.32) ALDH1A1GAASMN1; SMN2GCGR
SCHEMBL8480989 0.75 DPP4 (0.32) ALDH1A1GAASMN1; SMN2DPP4
SCHEMBL8479033 0.74 ACHE (0.33)
SCHEMBL8474810 0.73 MAPT (0.37) GAAHEXAHEXB
SCHEMBL8476218 0.72 GCGR (0.33) ALDH1A1GAASMN1; SMN2DPP4GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6004988-A Carboxylic acid derivatives, their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 1999-12-21 US disclosed