Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479476 | 0.89 | KDM4E (0.36) | KMT2AMAPTACHEALDH1A1LMNA | |
| SCHEMBL8478725 | 0.87 | TP53 (0.35) | KMT2AACHEALDH1A1TSHRTP53 | |
| SCHEMBL8474843 | 0.84 | KDM4E (0.39) | KMT2APOLBMAPTACHEALDH1A1 | |
| SCHEMBL8480167 | 0.76 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8478228 | 0.76 | MAPK1 (0.35) | KMT2AMAPTL3MBTL1KDM4EPTGS2 | |
| SCHEMBL8480800 | 0.76 | ACHE (0.35) | KMT2AMAPTACHEALDH1A1TSHR | |
| SCHEMBL8480989 | 0.75 | DPP4 (0.32) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8477575 | 0.74 | PDE4B (0.40) | GAA | |
| SCHEMBL8482102 | 0.72 | GCGR (0.32) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8481466 | 0.71 | PDE4B (0.36) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |