Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173901 | 0.82 | SCN9A (0.49) | KMT2AKDM4EALDH1A1THRBMAPT | |
| SCHEMBL8360539 | 0.78 | SCN9A (0.46) | KMT2AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL146186 | 0.76 | SCN9A (0.44) | KMT2AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL146859 | 0.76 | SCN9A (0.66) | ALDH1A1EGFRCREBBPL3MBTL1 | |
| SCHEMBL8482779 | 0.74 | HTR6 (0.54) | KMT2AKDM4EALDH1A1THRBHTR6 | |
| SCHEMBL28493427 | 0.73 | ALDH1A1 (0.58) | KMT2AKDM4EALDH1A1THRBHTR6 | |
| SCHEMBL4326615 | 0.72 | SCN9A (0.49) | KMT2AKDM4EALDH1A1MAPTMEN1 | |
| Methyl 4-Methoxybenzoate SCHEMBL28249391 | 0.72 | CA1 (0.84) | KMT2AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL6701016 | 0.71 | CA1 (0.65) | KMT2AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL8482994 | 0.71 | DYRK1A (0.58) | KMT2AKDM4EALDH1A1THRBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936098-A | Process for producing indoline compounds and intermediates for the production of the same | TOKYO TANABE COMPANY LIMITED (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0810214-A1 | PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |