Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.49 |
| ▸ | CPT2 | P23786 | 1/20 | 0.49 |
| ▸ | CPT1A | P50416 | 1/20 | 0.49 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4342789 | 0.87 | CPT2 (0.44) | SCN9ACPT2CPT1ACPT1BEGFR | |
| SCHEMBL13577941 | 0.86 | ASH1L (0.48) | SCN9ACPT2CPT1ACPT1BEGFR | |
| SCHEMBL4333426 | 0.85 | ALDH1A1 (0.48) | SCN9AEGFRF2RL3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4326712 | 0.85 | ASH1L (0.47) | SCN9ACPT2CPT1ACPT1BEGFR | |
| SCHEMBL4324539 | 0.84 | SCN9A (0.44) | SCN9ACPT2CPT1ACPT1BEGFR | |
| SCHEMBL4328324 | 0.84 | F2RL3 (0.53) | SCN9ACPT2CPT1ACPT1BF2RL3 | |
| SCHEMBL4330806 | 0.83 | CAMK2D (0.45) | SCN9AEGFRF2RL3MEN1KMT2A | |
| SCHEMBL146859 | 0.82 | SCN9A (0.66) | SCN9AEGFRPTGS2HPGDTDP1 | |
| SCHEMBL173901 | 0.81 | SCN9A (0.49) | SCN9AEGFRMEN1KMT2APTGS2 | |
| SCHEMBL13577950 | 0.80 | MAPK1 (0.45) | SCN9AMEN1KMT2ACNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |