Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.56 |
| ▸ | CES2 | O00748 | 6/20 | 0.54 |
| ▸ | CES1 | P23141 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484815 | 1.00 | HDAC1 (0.56) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8482201 | 0.94 | CES2 (0.51) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8409999 | 0.84 | L3MBTL1 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8408111 | 0.84 | L3MBTL1 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8408930 | 0.82 | L3MBTL1 (0.56) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8485994 | 0.81 | HDAC3 (0.48) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| Catechol SCHEMBL380042 | 0.79 | CES2 (0.62) | CES2CES1 | |
| Dodecanoate SCHEMBL28056278 | 0.77 | GPR84 (0.63) | HDAC11CES2CES1POLBCYP1A2 | |
| Biphenyl SCHEMBL7778554 | 0.77 | KMT2A (0.61) | HDAC11CES2CES1POLBSOAT1 | |
| Behenic Acid SCHEMBL8855897 | 0.77 | GPR84 (0.68) | HDAC11CES2CES1POLBSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874473-A | OSTEOPOROSIS; ANTIARTHRITIC AGENTS | BAYER CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |