Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27629358 | 0.91 | ALOX5 (0.78) | ALOX5HDAC6 | |
| SCHEMBL8827882 | 0.83 | ALOX5 (0.80) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL9430158 | 0.83 | ALOX5 (0.80) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL8827857 | 0.83 | ALOX5 (0.80) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL9431826 | 0.83 | ALOX5 (0.80) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL9124326 | 0.83 | ALOX5 (0.80) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL8799518 | 0.82 | ALOX5 (0.79) | ALOX5HDAC6ALOX5AP | |
| SCHEMBL26838881 | 0.81 | ALOX5 (0.84) | ALOX5HDAC6 | |
| SCHEMBL9154289 | 0.81 | ALOX5 (0.75) | ALOX5HDAC6 | |
| SCHEMBL9151239 | 0.81 | ALOX5 (0.75) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925646-A | Heterocyclic aryl-, alkyl- and cycloalkylacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-20 | — | — | US | disclosed |
| US-5747505-A | Heterocyclic aryl-, alkyl- and cycloalkylacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-05 | — | — | US | disclosed |