Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | CCR8 | P51685 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016195 | 0.93 | EGFR (0.69) | EGFRLTA4HCCR8PKMNPSR1 | |
| SCHEMBL11454925 | 0.85 | LMNA (0.54) | LTA4HMAPTALDH1A1THRB | |
| SCHEMBL4024133 | 0.85 | BCHE (0.62) | EGFRLTA4H | |
| SCHEMBL5852484 | 0.85 | KCNH2 (0.64) | EGFRLTA4HCCR8ALDH1A1THRB | |
| SCHEMBL24633513 | 0.84 | SMN1; SMN2 (0.60) | EGFRLTA4HALDH1A1 | |
| SCHEMBL9058678 | 0.84 | HTR4 (0.48) | EGFR | |
| SCHEMBL26454342 | 0.84 | EGFR (0.59) | EGFRLTA4HCCR8PKMNPSR1 | |
| SCHEMBL6222665 | 0.83 | EGFR (0.59) | EGFRLTA4HCCR8PKMNPSR1 | |
| SCHEMBL1222524 | 0.83 | ALDH1A1 (0.59) | ALDH1A1 | |
| SCHEMBL7247107 | 0.82 | KCNH2 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922717-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |