Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477428 | 0.88 | PTGS2 (0.40) | PTGS2PTGS1KDM4EMAPTPDGFRB | |
| SCHEMBL8475140 | 0.81 | PTGS2 (0.36) | PTGS2PTGS1GABRA1GABRB2ALOX5 | |
| SCHEMBL8477965 | 0.76 | MAPT (0.39) | PTGS2MAPT | |
| SCHEMBL8474934 | 0.76 | BCL2L2 (0.33) | PTGS2PTGS1GABRA1GABRB2ALOX5 | |
| SCHEMBL8474261 | 0.74 | MGAM (0.42) | MAPK1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8478421 | 0.74 | ALDH1A1 (0.36) | PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL8479043 | 0.74 | MAPK1 (0.37) | PTGS2PTGS1GABRA1GABRB2ALOX5 | |
| SCHEMBL8581095 | 0.73 | MAPK1 (0.36) | PTGS2PTGS1GABRA1GABRB2ALOX5 | |
| SCHEMBL8475168 | 0.73 | MAPK1 (0.39) | PTGS2PTGS1GABRA1GABRB2ALOX5 | |
| SCHEMBL8581223 | 0.73 | MAPK1 (0.36) | PTGS2PTGS1GABRA1GABRB2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |