Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478576 | 0.90 | KDM4E (0.37) | MAPK1MAPTKDM4EPDGFRBPDGFRA | |
| SCHEMBL8474084 | 0.89 | S1PR1 (0.37) | MAPK1MAPTKDM4EPDGFRBPDGFRA | |
| SCHEMBL8474672 | 0.82 | NPC1 (0.34) | MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL8474956 | 0.81 | KDM4E (0.40) | MAPTKDM4EPDGFRBPDGFRAPTGS2 | |
| SCHEMBL8475225 | 0.80 | MAPT (0.44) | MAPTKDM4EPTGS2 | |
| SCHEMBL8583542 | 0.77 | KDM4E (0.41) | MAPK1MAPTKDM4EPDGFRBPDGFRA | |
| SCHEMBL8480427 | 0.73 | PTGS2 (0.39) | MAPK1MAPTKDM4EPDGFRBPDGFRA | |
| SCHEMBL8479043 | 0.73 | MAPK1 (0.37) | MAPK1MAPTKDM4EPDGFRBPDGFRA | |
| SCHEMBL8581095 | 0.72 | MAPK1 (0.36) | MAPK1MAPTKDM4EPDGFRBPDGFRA | |
| SCHEMBL8475140 | 0.72 | PTGS2 (0.36) | MAPK1MAPTKDM4EPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |