Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.42 |
| ▸ | DHFR | P00374 | 2/20 | 0.39 |
| ▸ | HEXA | P06865 | 1/20 | 0.39 |
| ▸ | HEXB | P07686 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474820 | 0.88 | DHFR (0.41) | GCGRDHFRHEXAHEXBPTGS1 | |
| SCHEMBL8480104 | 0.87 | HEXA (0.40) | GCGRHEXAHEXBUSP7ALDH1A1 | |
| SCHEMBL8474990 | 0.85 | DHFR (0.44) | GCGRDHFRHEXAHEXBPTGS1 | |
| SCHEMBL8475512 | 0.81 | BRD4 (0.35) | GCGRTDP1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL8480049 | 0.78 | PDE4B (0.36) | PTGS2TDP1L3MBTL1NPC1GAA | |
| SCHEMBL8478069 | 0.76 | HEXA (0.44) | GCGRDHFRHEXAHEXBPTGS1 | |
| SCHEMBL8474614 | 0.71 | HEXA (0.46) | HEXAHEXBPTGS2KDM4ENPC1 | |
| SCHEMBL8478772 | 0.70 | BRD4 (0.36) | GCGRDHFRALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL8479260 | 0.69 | TP53 (0.41) | GCGRDHFRHEXAHEXBPTGS1 | |
| SCHEMBL8479432 | 0.67 | GCGR (0.41) | GCGRPTGS1PTGS2USP7TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |