Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478772 | 0.85 | BRD4 (0.36) | BRD4CHEK1AKT2BRD2SMN1; SMN2 | |
| SCHEMBL8479260 | 0.81 | TP53 (0.41) | BRD4CHEK1AKT2BRD2SMN1; SMN2 | |
| SCHEMBL8480559 | 0.81 | GCGR (0.42) | SMN1; SMN2MAPTALDH1A1GAAHPGD | |
| SCHEMBL8480049 | 0.80 | PDE4B (0.36) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL8475027 | 0.73 | BRD4 (0.42) | BRD4CHEK1AKT2BRD2SMN1; SMN2 | |
| SCHEMBL8480104 | 0.71 | HEXA (0.40) | ALDH1A1KDM4ENPC1RAB9AGCGR | |
| SCHEMBL8478757 | 0.68 | MAPT (0.44) | MAPTGAANPC1RAB9APOLB | |
| SCHEMBL8477304 | 0.68 | PDCD1 (0.38) | ALDH1A1GAAHPGDNPC1RAB9A | |
| SCHEMBL8474820 | 0.68 | DHFR (0.41) | SMN1; SMN2MAPTALDH1A1GAAHPGD | |
| SCHEMBL8474276 | 0.68 | TDP1 (0.34) | ALDH1A1GAAHPGDGCGRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |