Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812393 | 0.84 | ACHE (0.57) | CHRM4HRH3ACHEKDM4EALDH1A1 | |
| SCHEMBL8483963 | 0.82 | ACHE (0.57) | CHRM4HRH3ACHEKDM4EALDH1A1 | |
| SCHEMBL8483969 | 0.82 | ACHE (0.57) | HRH3ACHEKDM4EALDH1A1RECQL | |
| Hydrochloric Acid SCHEMBL8480704 | 0.81 | ALDH1A1 (0.59) | ACHEKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27561329 | 0.81 | CA12 (0.71) | ACHEKDM4EFAAH | |
| SCHEMBL1943453 | 0.78 | CCR2 (0.68) | KDM4ESMN1; SMN2FAAH | |
| SCHEMBL13443092 | 0.78 | ACHE (0.54) | ACHEKDM4EALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL13443303 | 0.77 | MC4R (0.60) | ACHEALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL3594265 | 0.77 | ALDH1A1 (0.56) | HRH3ACHEKDM4EALDH1A1KMT2A | |
| SCHEMBL3959065 | 0.76 | ACHE (0.66) | CHRM4HRH3ACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922717-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |