Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1526352 | 0.85 | CA1 (0.41) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL7838938 | 0.83 | CA1 (0.39) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL12817362 | 0.80 | ALOX5 (0.42) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8093384 | 0.79 | ABCB1 (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL5335645 | 0.79 | ALOX5 (0.49) | ALOX5PTGS2 | |
| SCHEMBL64882 | 0.79 | CA1 (0.42) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL28069112 | 0.77 | CA1 (0.41) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL6203845 | 0.77 | CA1 (0.41) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL4586248 | 0.77 | TAAR1 (0.41) | ENPP2CA1CA2CA12CA7 | |
| SCHEMBL7672336 | 0.76 | TUBB4A (0.50) | ALDH1A1KDM4EHPGDTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |