Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672336 | 0.87 | TUBB4A (0.50) | ABCB1SIGMAR1TAAR1HPGD | |
| SCHEMBL7664369 | 0.87 | NPC1 (0.37) | ABCB1ABCG2TAAR1 | |
| SCHEMBL8859963 | 0.84 | LTA4H (0.44) | ABCB1SIGMAR1HPGDADRA1DADRA1A | |
| SCHEMBL7673923 | 0.83 | ABCB1 (0.52) | ABCB1ABCG2SIGMAR1TAAR1 | |
| SCHEMBL7838938 | 0.80 | CA1 (0.39) | SIGMAR1ALOX5TAAR1CA12CA1 | |
| SCHEMBL8480841 | 0.79 | ENPP2 (0.38) | ALOX5TAAR1HPGDCA12CA1 | |
| SCHEMBL7668280 | 0.79 | MAPT (0.46) | ABCB1 | |
| SCHEMBL4586248 | 0.78 | TAAR1 (0.41) | TAAR1HPGDCA12CA1CA2 | |
| SCHEMBL12817362 | 0.77 | ALOX5 (0.42) | ALOX5CA12CA1CA2CA4 | |
| SCHEMBL715204 | 0.77 | KCNH2 (0.41) | TAAR1KCNH2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |