SCHEMBL848175

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL847650	0.89	PTH1R (0.59)	PTH1RMGLLSLC6A7HSD11B1
	SCHEMBL848494	0.85	PTH1R (0.43)	PTH1RMGLLSLC6A7HSD11B1GHSR
	SCHEMBL848493	0.85	PTH1R (0.43)	PTH1RMGLLSLC6A7HSD11B1GHSR
	SCHEMBL849849	0.84	PTH1R (0.51)	PTH1RMGLLSLC6A7HSD11B1GHSR
	SCHEMBL13553743	0.83	PTH1R (0.49)	PTH1RSCN9A
	SCHEMBL848082	0.83	PTH1R (0.60)	PTH1RMGLLSLC6A7GHSR
	SCHEMBL850040	0.82	PTH1R (0.67)	PTH1RSCN9A
	SCHEMBL849397	0.82	MGLL (0.42)	PTH1RMGLLSLC6A7HSD11B1GHSR
	SCHEMBL849396	0.82	MGLL (0.42)	PTH1RMGLLSLC6A7HSD11B1GHSR
	SCHEMBL850963	0.82	PTH1R (0.58)	PTH1RMGLLSLC6A7HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.