Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948606 | 0.84 | MTNR1A (0.70) | MTNR1AMTNR1B | |
| Cyclopropane SCHEMBL6950925 | 0.82 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL7557533 | 0.80 | MTNR1A (0.73) | MTNR1AMTNR1B | |
| SCHEMBL8481998 | 0.79 | MTNR1A (0.67) | MTNR1AMTNR1BDRD2DRD3 | |
| SCHEMBL6948988 | 0.79 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| Cyclopropane SCHEMBL6952617 | 0.77 | MTNR1A (0.51) | MTNR1AMTNR1B | |
| SCHEMBL8611672 | 0.76 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL31561748 | 0.74 | MTNR1A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL6676720 | 0.73 | MTNR1B (0.74) | MTNR1AMTNR1BDRD2HTR2ADRD3 | |
| SCHEMBL7697605 | 0.73 | MTNR1B (0.74) | MTNR1AMTNR1BDRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | claimed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | claimed |
| EP-0901483-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1999-03-17 | — | — | EP | claimed |
| WO-1997043272-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1997-11-20 | — | — | WO | claimed |
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0901483-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043272-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |