Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
| ▸ | MC1R | Q01726 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482140 | 0.77 | LTA4H (0.50) | MMP9CTNNB1TDP1METAP2HRH4 | |
| SCHEMBL10477663 | 0.77 | CYP1A2 (0.41) | MMP9CTNNB1TDP1HRH4MME | |
| SCHEMBL6677809 | 0.75 | CTNNB1 (0.63) | CTNNB1TDP1HRH4MMEACE | |
| SCHEMBL28049380 | 0.74 | CYP2D6 (0.61) | TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10477863 | 0.73 | CTNNB1 (0.45) | MMP9CTNNB1TDP1METAP2HRH4 | |
| SCHEMBL4069695 | 0.73 | TDP1 (0.50) | MMP9CTNNB1TDP1HRH4MME | |
| SCHEMBL10756689 | 0.73 | CTNNB1 (0.50) | MMP9CTNNB1TDP1METAP2HRH4 | |
| SCHEMBL10338654 | 0.73 | CPA1 (0.57) | CTNNB1TDP1HRH4MMEACE | |
| SCHEMBL3814684 | 0.73 | CTNNB1 (0.56) | MMP9CTNNB1TDP1HRH4MME | |
| SCHEMBL9194477 | 0.73 | CPA1 (0.57) | CTNNB1TDP1HRH4MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008372-A | ANTICARCINOGENIC, ANTIRESTENOSIS AND ANTIPSORIASIS AGENT | WARNER-LAMBERT COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| WO-1997026246-A1 | SUBSTITUTED HISTIDINE INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |