Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677809 | 0.79 | CTNNB1 (0.63) | CTNNB1MMEACECPA1ACE2 | |
| SCHEMBL7287691 | 0.78 | CTNNB1 (0.58) | CTNNB1MMEACECPA1ACE2 | |
| SCHEMBL7268294 | 0.78 | CTNNB1 (0.58) | CTNNB1MMEACECPA1ACE2 | |
| SCHEMBL7267021 | 0.78 | CTNNB1 (0.58) | CTNNB1MMEACECPA1ACE2 | |
| SCHEMBL8482142 | 0.77 | MMP9 (0.50) | CTNNB1MMP9MMEACECPA1 | |
| SCHEMBL10477689 | 0.77 | KDM4E (0.44) | CTNNB1MMP9MMEACECPA1 | |
| SCHEMBL3814684 | 0.77 | CTNNB1 (0.56) | CTNNB1MMP9MMEACECPA1 | |
| SCHEMBL10756689 | 0.77 | CTNNB1 (0.50) | CTNNB1MMP9MMEACECPA1 | |
| SCHEMBL16017641 | 0.76 | CTNNB1 (0.59) | CTNNB1MMP9MMEACECPA1 | |
| SCHEMBL6907446 | 0.76 | CTNNB1 (0.59) | CTNNB1MMP9MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008372-A | ANTICARCINOGENIC, ANTIRESTENOSIS AND ANTIPSORIASIS AGENT | WARNER-LAMBERT COMPANY (US) | 1999-12-28 | — | — | US | disclosed |