SCHEMBL8482144

SCHEMBL8482144

[CH2]c1c(CO)cccc1[N+](=O)[O-]

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 3/20 0.50
GPR35 Q9HC97 2/20 0.48
CA12 O43570 1/20 0.47
HPGD P15428 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PTPN1 P18031 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PDE10A Q9Y233 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27942397 0.81 ALDH1A1 (0.47) ALDH1A1TSHRTDP1GPR35HPGD
SCHEMBL68381 0.80 ALDH1A1 (0.70) ALDH1A1TSHRTDP1GPR35CA12
SCHEMBL29699944 0.80 ALDH1A1 (0.70) ALDH1A1TSHRTDP1GPR35CA12
SCHEMBL83317 0.80 TDP1 (0.61) ALDH1A1TSHRTDP1GPR35MEN1
SCHEMBL3933610 0.79 GPR35 (0.58) ALDH1A1TSHRTDP1GPR35CA12
SCHEMBL27671751 0.79 GPR35 (0.67) ALDH1A1TSHRTDP1GPR35CA12
SCHEMBL5622028 0.79 ALDH1A1 (0.53) ALDH1A1TSHRTDP1GPR35CA12
SCHEMBL27974292 0.79 ALDH1A1 (0.44) ALDH1A1TSHRTDP1GPR35HPGD
SCHEMBL30360988 0.79 ALDH1A1 (0.68) ALDH1A1TSHRTDP1GPR35CA12
Hydrochloric Acid SCHEMBL27731300 0.79 ALDH1A1 (0.68) ALDH1A1TSHRTDP1GPR35CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5856334-A ANTAGONIST FOR EOSINOPHILS MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1999-01-05 US disclosed
EP-0773219-A1 IMIDAZOQUINOLINE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1997-05-14 EP disclosed