SCHEMBL8482180

SCHEMBL8482180

CCOc1ccccc1CNC(=S)c1ccc2cccnc2n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
THRB P10828 2/20 0.43
TP53 P04637 2/20 0.42
ALDH1A1 P00352 5/20 0.41
KMT2A Q03164 6/20 0.41
MEN1 O00255 5/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
MAPT P10636 3/20 0.41
ATM Q13315 2/20 0.41
GAA P10253 2/20 0.41
POLB P06746 2/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
PLEC Q15149 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ALOX15 P16050 2/20 0.40
USP2 O75604 1/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7018462 0.90 KMT2A (0.52) LMNAALDH1A1KMT2AMEN1POLB
SCHEMBL8481976 0.87 TAS1R3 (0.47) LMNAALDH1A1KMT2AMEN1MAPT
SCHEMBL6640865 0.80 MEN1 (0.47) LMNATHRBALDH1A1KMT2AMEN1
SCHEMBL8476748 0.78 TRPV1 (0.41) LMNAALDH1A1KMT2AMEN1MAPT
SCHEMBL7016470 0.76 MEN1 (0.71) LMNAALDH1A1KMT2AMEN1MAPT
SCHEMBL7840550 0.76 MEN1 (0.52) LMNAALDH1A1KMT2AMEN1POLB
SCHEMBL7015349 0.73 MEN1 (0.55) LMNAALDH1A1KMT2AMEN1MAPT
SCHEMBL7010073 0.73 MEN1 (0.52) LMNATP53ALDH1A1KMT2AMEN1
SCHEMBL8475706 0.72 LMNA (0.51) LMNATHRBTP53ALDH1A1KMT2A
SCHEMBL7014525 0.71 MEN1 (0.52) LMNAKMT2AMEN1POLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5945431-A VIRICIDE BIOCHEM THERAPEUTICS INCORPORATED (CA) 1999-08-31 US disclosed