Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 2/20 | 0.43 |
| ▸ | PRKX | P51817 | 2/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010267 | 0.87 | LMNA (0.61) | LMNAMAPTTP53THRBSUCNR1 | |
| SCHEMBL8138354 | 0.80 | MAOB (0.44) | LMNAMAPTTP53THRBSUCNR1 | |
| SCHEMBL7019353 | 0.79 | MAPT (0.57) | LMNAMAPTTP53THRBSUCNR1 | |
| SCHEMBL7018462 | 0.77 | KMT2A (0.52) | LMNAHPGDKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28042144 | 0.75 | MAPK8 (0.51) | LMNAMAPTTP53THRBHPGD | |
| SCHEMBL617423 | 0.74 | KMT2A (0.62) | LMNAMAPTTP53THRBHPGD | |
| SCHEMBL7014947 | 0.74 | EGLN1 (0.64) | LMNAMAPTSUCNR1HPGDKMT2A | |
| SCHEMBL3815751 | 0.72 | SMN1; SMN2 (0.72) | LMNAMAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL8482180 | 0.72 | LMNA (0.43) | LMNAMAPTTP53THRBKMT2A | |
| SCHEMBL7010262 | 0.71 | KMT2A (0.59) | LMNAMAPTTP53THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945431-A | VIRICIDE | BIOCHEM THERAPEUTICS INCORPORATED (CA) | 1999-08-31 | — | — | US | disclosed |